Sinus culture poorly predicts resident microbiota

Background: Chronic rhinosinusitis (CRS) is an inflammatory disorder of the paranasal sinuses in which bacteria are implicated. Culture-based assays are commonly used in clinical and research practice; however, culture conditions may not accurately detect the full range of microorganisms present in a sample. The objective of this study was to determine the accuracy of clinical

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Determining the utility of standard hospital microbiology testing: Comparing standard microbiology cultures with DNA sequence analysis in patients with chronic sinusitis

Introduction Chronic rhinosinusitis (CRS) is an inflammatory condition of the mucosal lining of the nasal cavities and paranasal sinuses that affects both children and adults. When the inflammation persists beyond twelve weeks, a diagnosis of CRS is established. CRS is a multifactorial inflammatory process and when superimposed with infection, the inflammation becomes more complex and

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